You don't have to be nervous. Just understand you will be slow up some steep grades.
I own a 1987 4 cyl/auto Sunrader and just returned from a 1 month, 4,000 mile trip from western NY state through St. Louis to Wichita, KS, Oklahoma, into Mississippi, through the Arkansas Ozark Mountains, Tennnesee, Kentucky and West Virginia.
Saw a lot and didn't have any troubles at all.